Home Therapy Heart and thorax
Home Therapy Heart and thorax

endocarditis, natieve klep - HACEK

Advices

≥ 18 years
Priority Medication Remarks
Medication:

ceftriaxon iv 2000mg 2dd 1 days

followed by

ceftriaxon iv 2000mg 1dd 4 weeks
Remarks:

Empirisch
Ook indien verwekker beta-lactamase positief
Ook bij penicilline allergie
Medication:

amoxicilline iv loading dose 2g, 12g continuous per 24 hours 4 weeks
Remarks:

Indien verwekker beta-lactamase negatief
Medication:

ciprofloxacine iv 400mg 2dd 4 weeks

or

ciprofloxacine po 500mg 2dd 4 weeks
Remarks:

Bij beta-lactam allergie

General comments

Overleg met endocarditis-team (internist-infectioloog of arts-microbioloog)

Advies ongewijzigd gepubliceerd na beoordeling in kader van revisie SWABID UMCG in opdracht van CAM 1-8-2022

Sources

  1. SWAB Richtlijn Infectieuze Endocarditis
  2. Endocarditis protocol UMCG
  3. European Society of Cardiology (ESC): Infective Endocarditis (Guidelines on Prevention, Diagnosis and Treatment of)
  4. Pubmed.gov publication # 26373316

    Circulation. 2015 Oct 13;132(15):1435-86.

    Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications A Scientific Statement for Healthcare Professionals From the American Heart Association.

  5. Pubmed.gov publication # 19713420

    Eur Heart J. 2009 Oct;30(19):2369-413.

    Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009): the Task Force on the Prevention, Diagnosis, and Treatment of Infective Endocarditis of the European Society of Cardiology (ESC). Endorsed by the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and the International Society of Chemotherapy (ISC) for Infection and Cancer.

  6. Pubmed.gov publication # 22086858

    J Antimicrob Chemother. 2012 Feb;67(2):269-89.

    Guidelines for the diagnosis and antibiotic treatment of endocarditis in adults: a report of the Working Party of the British Society for Antimicrobial Chemotherapy.

Antimicrobial resources

The following antimicrobial agents have been used in these recommendations:

External antimicrobial resources
Menu position
Metadata

Swab vid: G-211184.9
Updated: 11/30/2022 - 12:32
Status: Published