Home Therapy Heart and thorax
Home Therapy Heart and thorax

endocarditis, natieve klep/kunstklep - enterokokken

Advices

≥ 18 years

Indications: Amoxicilline gevoelig
Priority Medication Remarks
Medication:

amoxicilline iv loading dose 2g, 12g continuous per 24 hours 6 weeks

+

ceftriaxon iv 2000mg 2dd 6 weeks
≥ 18 years

Indications: Resistentie tegen amoxicilline of penicillineallergie, én GEEN high level gentamicine resistentie [HLAR]
Priority Medication Remarks
Medication:

vancomycine iv loading dose 20mg/kg, 30mg/kg continuous per 24 hours 6 weeks

+

gentamicine iv 3mg/kg 1dd 4 weeks
Remarks:

Vancomycine continue-dosering op geleide van TDM, zie Opmerkingen

 

Indien HLAR voor gentamicine wordt vancomycine monotherapie gegeven

Vancomycine: na de oplaaddosering wordt direct vervolgd met continue infusie/24 uur

General comments

Overleg met endocarditis-team (internist-infectioloog of arts-microbioloog)

Advies opnieuw gepubliceerd na beoordeling in kader van revisie SWABID UMCG in opdracht van CAM 1-8-2022

Sources

  1. SWAB Richtlijn Infectieuze Endocarditis
  2. Endocarditis protocol UMCG
  3. European Society of Cardiology (ESC): Infective Endocarditis (Guidelines on Prevention, Diagnosis and Treatment of)
  4. Pubmed.gov publication # 19713420

    Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009): the Task Force on the Prevention, Diagnosis, and Treatment of Infective Endocarditis of the European Society of Cardiology (ESC). Endorsed by the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and the International Society of Chemotherapy (ISC) for Infection and Cancer. Eur Heart J. 2009 Oct;30(19):2369-413.

  5. Pubmed.gov publication # 22086858

    Guidelines for the diagnosis and antibiotic treatment of endocarditis in adults: a report of the Working Party of the British Society for Antimicrobial Chemotherapy. J Antimicrob Chemother. 2012 Feb;67(2):269-89.

  6. Pubmed.gov publication # 17438316

    Gavaldà J, et al. Brief communication: treatment of Enterococcus faecalis endocarditis with ampicillin plus ceftriaxone. Ann Intern Med. 2007 Apr 17;146(8):574-9.

Antimicrobial resources

The following antimicrobial agents have been used in these recommendations:

External antimicrobial resources
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Metadata

Swab vid: G-211115.9
Updated: 11/30/2022 - 12:01
Status: Published